Plus 2 Lecturer Mixed Practice Test #730

Question 1

The primary mechanism by which non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen cause gastric ulceration is:

Accepted Answer

B. Inhibition of cyclooxygenase-1 (COX-1) in the gastric mucosa. — NSAIDs inhibit cyclooxygenase (COX) enzymes. Inhibition of COX-1 in the gastric mucosa reduces the production of protective prostaglandins, which are essential for maintaining gastric blood flow, mucus secretion, and bicarbonate production, thereby leading to mucosal damage and ulceration.

Answer

A. Direct corrosive action on the gastric mucosa.

Answer

C. Increased gastric acid secretion.

Answer

D. Stimulation of histamine release in the stomach.

Question 2

Normal body temp:‌​‍

Accepted Answer

37°C — 37°C (98.6°F).‌​‍

Answer

36°C

Answer

38°C

Answer

39°C

Question 3

Flipkart founders:‌​‍

Accepted Answer

Sachin and Binny Bansal — Bansal pair.‌​‍

Answer

Bhavish

Answer

Others

Answer

VSS

Question 4

Volume of a cuboid with dimensions 4×3×5 cm is:

Accepted Answer

60 cm³ — V = l×b×h = 4×3×5 = 60 cm³.

Answer

12 cm³

Answer

15 cm³

Answer

80 cm³

Question 5

COVID-19 vaccines in India:‌​‍

Accepted Answer

All three and more — Covaxin, Covishield, Sputnik V, Corbevax, etc.‌​‍

Answer

Covaxin, Covishield

Answer

Only Covaxin

Answer

Sputnik also

Question 6

Edakkal Caves in:‌​‍

Accepted Answer

Wayanad — Ancient petroglyphs.‌​‍

Answer

Thrissur

Answer

Idukki

Answer

Palakkad

Question 7

Kottayam is known as:‌​‍

Accepted Answer

Rubber capital — Rubber capital of India.‌​‍

Answer

Spice garden

Answer

Cashew capital

Answer

Rice bowl

Question 8

A patient diagnosed with schizophrenia exhibits flat affect, alogia, and avolition. These symptoms are primarily categorized as:

Accepted Answer

B. Negative symptoms — Negative symptoms of schizophrenia involve a loss or decrease in normal functions and behaviors, such as flat affect (lack of emotional expression), alogia (poverty of speech), and avolition (lack of motivation). Positive symptoms, in contrast, are an excess or distortion of normal functions, like hallucinations and delusions.

Answer

A. Positive symptoms

Answer

C. Cognitive symptoms

Answer

D. Affective symptoms

Question 9

Which of the following functional groups is primarily responsible for the antibacterial activity of penicillin antibiotics?

Accepted Answer

C. Beta-lactam ring — The beta-lactam ring is crucial for the antibacterial activity of penicillins and other beta-lactam antibiotics. It irreversibly inhibits bacterial transpeptidases (penicillin-binding proteins), preventing cell wall synthesis. The other components contribute to the drug's overall structure and pharmacokinetics but are not the primary pharmacophore for antimicrobial action.

Answer

A. Carboxyl group

Answer

B. Thiazolidine ring

Answer

D. Amide linkage

Question 10

SHG model in Kerala:

Accepted Answer

Kudumbashree (~46 lakh members) — Massive grassroots network.

Answer

Few members

Answer

Urban only

Answer

Rural only

Plus 2 Lecturer Mixed Practice Test #730